Ibyiza bya Capsule

Mu 1500 mbere ya Yesu, capsule ya mbere yavukiye mu Misiri.

Mu 1730, abafarumasiye i Vienne batangiye gukora capsules ziva muri krahisi.

Mu 1834, tekinoroji yo gukora capsule yatanzwe i Paris.

Mu 1846, tekinoroji yibice bibiri ikora tekinoroji ya capsule yaguzwe mubufaransa Patents.

Mu 1848, capsules ibice bibiri yasohotse. Kuva icyo gihe, ibishishwa bya capsule byubusa byinjiye mu buvuzi maze biba ibikoresho byo gupakira imiti.

Mu 1874, i Detroit hatangijwe inganda zikomeye za capsules (Hubel), kandi moderi zitandukanye zatangijwe icyarimwe.

Mu 1888, Parke-Davis yabonye ipatanti yo gukora capsules zikomeye muri Detroit (JB Russell)

Mu 1931, umuvuduko wo gukora capsule ya Parke-Davis wageze kuri capsules 10,000 ku isaha (A. Colton)

Nibikoresho byiza byo gupakira imiti, Ubusa capsule shell ikoreshwa cyane mugutegura imiti. Zikwirakwizwa cyane mubifu, amazi, igice-gikomeye, amavuta, ibinini nibindi byateguwe. Birashobora kwihuta, kwizerwa no kubora neza. Bafite ibyiza bikurikira:

1) Ubwiza bwiza kandi bworoshye kumira.

2) Ingaruka ya Masking: Irashobora guhisha umururazi numunuko utameze neza wibiyobyabwenge, kandi ikarinda kandi igahindura ibintu bitajegajega.

3) Bioavailable nyinshi yibiyobyabwenge: Capsules ntisaba gufatira hamwe nigitutu mugihe cyo kwitegura nkibinini n'ibinini, bityo bigatatana vuba kandi bikinjira neza munda no munda.

4) Kurinda neza ibikomoka ku bimera: Hatariho ubushyuhe bwinshi n’umuvuduko mwinshi uzanwa n’ibikoresho bya tablet, imiterere karemano yimiti yimiti yibihingwa muri capsule irashobora kugumaho.

5) Irashobora gukorwa mubikorwa byo gukomeza-kurekura no gutegura ibice:

Umuti urashobora kurekurwa mugihe cyagenwe (enteric-coated, pulsed nubundi buryo bwo kurekura ibiyobyabwenge). Niba imiti yabanje gukorwa mubice, hanyuma ibikoresho bya gelatin nibikoresho bifite ibipimo bitandukanye byo kurekura, ingaruka zigihe nigihe cyo kurekura zishobora kugerwaho. Kubwibyo, capsules nuburyo bwiza bwa dosiye yo guteza imbere imyiteguro irambye-irekura hamwe nimyiteguro.

6) Kwandika no gutegura biroroshye, byoroshye mubikorwa byinganda no gukora Automatic.