Indwara ya Hemostatike cyangwa urashobora no kuyita sponges yo kubaga, kubera gukoresha cyane kubaga kugirango wirinde kuva amaraso. Mu buryo nk'ubwo, bazwi kandi nka gukurura hemostatike gelatin spongeskuberako bikozwe mubintu bikurura nka selile, gelatine yamagufa, nibindi bikoresho bya polymeriki. Nyamara, ibyo bice bikora neza kugirango umubiri uhindurwe kugirango uhagarike kuva amaraso.
Sponge ikoreshwa mubuvuzi bwa neurosurgie, amenyo, otolaryngology, ginecology, hamwe no kubaga kugirango bahagarike kuva amaraso no gutwika igikomere. Hagati aho, sponge ya hemostatike itera imbaraga kuvugurura ingirabuzima fatizo kandi ikagira imiti igabanya ubukana.
Iyi nyandiko izasobanura icyo sponges ya hemostatike ikozwe nibikorwa byingenzi mubuvuzi.
Ibigize Hemostatike Sponge
Ibigize Spostes ya Hemostatike ni ngombwa mu guhagarika amaraso no gukora amaraso mu bikomere. Ibigize ni ibi bikurikira:
Ibikoresho by'ibanze ：
▶Imiti ya Gelatine:
Imitsi myinshi ya hemostatike irimo Imiti ya gelatine, poroteyine fatizo ikomoka ku magufa ya bovine. Ibi bovine amagufwa gelatinifite inyungu zitandukanye.
Absorbability:
Iyo ubuso bwayo bwinjije amaraso, burashobora gukora ibibyimba, bikarinda gutakaza amaraso.
▶Ibinyabuzima bigabanuka:
Iyi phenomenon isobanura ko iyo umubiri wumuntu usanzwe usenya gelatine, bifasha gukora amaraso, bigahagarika kuva amaraso.
▶Thrombin:
Thrombin ni enzyme itanga imbaraga zitaziguye kugirango itange amaraso.
▶Fibrinogen:
Poroteyine fibrinogen igira uruhare runini mu gukora amaraso.
Ibikoresho Byuzuza Hemostatike
Ibikoresho byuzuza Hemostatike bigabanijwemo ubwoko butatu bitewe nuburinganire n'imikorere yabyo: ibikoresho bishingiye kuri polysaccharide, reagent ya proteine ishingiye kuri poroteyine, hamwe n’imiti ikomoka ku miti.
1. Imiti ikomoka ku miti ivangwa na Hemostatike:
Imiti ya Hemostasis ni monomers ntoya cyangwa polymers zishobora kwitwara neza kugirango zibyare geles hamwe na tissue binders. Nubwo ibyo bikoresho bifite ibyago bike byo kwandura virusi kuruta ibicuruzwa bishingiye kuri poroteyine, ingorane zimwe na zimwe, hamwe n’ibibazo byinshi bituruka ku burozi bw’imiti no kutangirika bikomeje.2.
2.Abakozi ba Hemostatike: Bishingiye kuri poroteyine
Intungamubiri zishingiye kuri poroteyine, zigizwe na trombine, kolagen, cyangwa fibrinogen, zirasa nuburyo bwa EC / PGRF mubijyanye nigiciro kinini. Barashobora kwandura, ariko bafite igihe gito cyo kubaho. Intungamubiri zishingiye kuri poroteyine ni ingenzi mu gukumira amaraso mu kubaga. Izi mikorere zikora mukoresha proteine, nka fibrin cyangwa kolagen, byihutisha uburyo busanzwe bwo kwambara mumubiri.
Iyo izo poroteyine zikoreshwa mu gupfuka igikomere, zikora umwenda ukomeye uhagarika kuva amaraso kandi bikongera gukira. Kurwanya vuba kandi neza gutakaza amaraso nibyingenzi muburyo bwo kubaga no kuvura cyane, bitanga agaciro gakomeye kubintu bya poroteyine bishingiye kuri poroteyine. Nibinyabuzima bihuza kandi mubisanzwe bikorana neza na chimie yumubiri. Kubwibyo, kubavuzi, byahindutse uburyo bwiza bwo kongera ibihe byo gukira no kuzamura umusaruro wabarwayi.
3.Polimeri Hemostatike Ibikoresho bikomoka kuri Polysaccharide
Byubatswe cyane cyane muri selile, chitosan, sodium alginate, na krahisi. Uburyo ubwo aribwo bwose ubireba… birashobora gukora ibintu byose biva mubutaka munsi yizuba. Ubu bwoko bwa polymer buguha biocompatibilité nziza, biodegradabilite, nibiranga immunogenic.
Niki Bovine Amagufa Gelatin?
Bovine amagufwa gelatinni ubwoko bwiza bwa gelatine muburyo bwose bwa sponges. Bikomoka kumagufa yinka cyangwa andi magufa yinka kandi bifite inyungu nyinshi.
Hagati aho Bovine amagufwa gelatin ikurura neza amaraso, ikora uduce twinshi twaho duhagarika neza kuva amaraso. Gelatine igenda yangirika buhoro buhoro mumubiri, bikagabanya gukurwaho nyuma yo gukoreshwa.
Uburyo bwo Gukora Hemostatike Sponges
Indwara ya Hemostatike ni ngombwa mu kubaga no kuvura ibikomere, ariko imiterere yabyo n'ibigize bigira ingaruka zikomeye ku mikorere yabyo. Hano, turareba uburyo buke bwo gutegura ibi bikoresho byamaraso:
1.Gukonjesha-Kuma:
Ubu buryo bukoreshwa cyane burimo guhagarika igisubizo nyuma yimiterere ya hemostatike, akenshi gelatine, imaze gushonga mumashanyarazi. Ubukurikira, icyuho gihabwa uruvange rwahagaritswe, bigatuma umusemburo ugabanuka - kuva mu buryo butaziguye uva muri gaze ujya kuri gaze - utashonga urubura. Ibi bisenya urubura rwa kirisiti, hasigara imiterere ya sponge. Iyo ushyizwe mu gikomere, materique ya gelatine isigaye igumana ibintu bya hemostatike kandi bigatera gukora amaraso.
2.Gukemura ibibazo bya Solvent & Particular Leaching:
Ubwa mbere, umusemburo ushonga amagufwa gelatine nibindi bikoresho nka fibrinogen na trombine kugirango utangire inzira. Nyuma yibi, amazi arasohoka, ushobora gushiramo muburyo butandukanye hanyuma ukagenda mugihe runaka kugirango ukomere. Iyo bimaze gushyirwaho, umunyu cyangwa isukari bishonga hamwe na solde itandukanye. Nyuma yibi bikorwa byo kumeneka, ubona ibintu byoroshye bita hemostatike sponges, inzira nziza yo kwirinda kuva amaraso.
3.Amashanyarazi:
Ubu buryo bugezweho bukoresha amashanyarazi kugirango uhindure igisubizo cya polymer mumibiri yoroshye. Hagati aho, polymer igisubizo ni hemostatike sponges ikozwe mumagufa gelatine cyangwa izindi polymers. Iyo ushyize ibikoresho bisa na fibre kuri kolitori nyuma yo kugira umurima wamashanyarazi, ikora ibintu bimeze nka matel. Nuburyo bukora sponge ya hemostatike, ushobora gukoresha muburyo bwo kubaga.
4.Lyophilisation hamwe na Crosslinking:
Ubu buryo bukoresha ibikoresho bihuza hamwe no gukonjesha. Kwambukiranya kugenga igipimo cya sponge imbere kandi kigashimangira imiterere yacyo. Gelatin hamwe na agent ihuza ibintu bishonga mumashanyarazi hanyuma bikonjeshwa. Imiti ikora imiti ihuza molekile ya gelatine muri matrise yavuyemo ikonjesha, igashimangira sponge ya hemostatike kandi ikarekura kurekurwa.
Hagati aho, abashakashatsi bakomeje kuvumbura uburyo bushya bwo gukora sponges ya spostes yo kuvura. Nubwo imiterere ya sponges ishobora kuvugururwa kugirango ibahe gukoresha byinshi, nka mikorobe yica mikorobe, ubu bushakashatsi bugamije kubikoresha nk'uburyo bwa polimeri ishingiye ku bimera. Nyamara, intego yibanze nugukora sponges nyinshi zifite umutekano, zifite akamaro, kandi zigezweho.
Gukuramo no gutunganya amagufwa ya Gelatin
Inzira yo gukuramo amagufwa gelatine ikubiyemo intambwe zimwe na zimwe nka:
Amagufa y'inka agurwa n'abacuruzi bizewe kandi akorerwa igenzura rikomeye kugirango yizere neza.
Imiti cyangwa imisemburo ikoreshwa mugukuramo kolagene, proteine yibanze yamagufwa.
Kolagen yakuweho ikorerwa inzira ikomeye yo kweza ikuraho umwanda kugirango igere kumitungo ikenewe kuri gelatine yo mu rwego rwa farumasi.
Gelatine yanyuma ihagarikwa kugirango ikureho bagiteri na virusi.
Inyungu za Hemostatike Sponge
Sponges ya hemostatike yagenewe gukumira gutakaza amaraso menshi mubyumba byo gukoreramo no kongera imbaraga zo kurema uturemangingo kugirango umubiri wumuntu ubashe kwikiza vuba kandi neza.
Itezimbere Kwihuta no Gukiza Ibikomere
Sponges ya hemostatike ifite inyungu nyinshi, nko guhagarika kuva amaraso kubikomere, kumena amaraso, no gutangira kurema ibibyimba. Iyi miti izamura umubiri wumuntu imbaraga zo gukiza no gukiza umurwayi gutakaza amaraso menshi mugihe habaye kubagwa.
✔Ifasha Kurwanya Amaraso Mugihe cyo Kubaga
Indwara ya Hemostatike ikoreshwa mugukumira amaraso mugihe cyo kubaga ibintu bitandukanye. Birashobora gukoreshwa muburyo butaziguye kuva amaraso kugirango bitume habaho imitsi kandi bitange ubufasha bwubukanishi. Ibi bigabanya amahirwe yingorane kandi bitezimbere muri rusange uburyo bwo kubaga mugukomeza umurima wubusa.
✔Kugabanya Gutakaza Amaraso kandi Kugabanya Ingaruka Zibibazo
Sponges ya hemostatike ihagarika gutakaza amaraso hamwe ningaruka ziterwa nibibazo mugukosora neza ibikomere byamaraso. Kuberako gutakaza amaraso menshi bishobora gutera abarwayi kujya muri koma cyangwa bagashira, uyu murokore uhora ari ngombwa muburyo bwose bwo kubagwa.
Ikoreshwa rya Hemostatike Sponges mubuvuzi
Sponges ya Hemostatike ifite uburyo butandukanye mubuvuzi bwo kurwanya amaraso:
iKoresha mu Kubaga Kugenzura Amaraso
Zikoreshwa neza muburyo bwinshi bwo kubaga kugirango birinde gutakaza amaraso. Uburyo gakondo, nka ligature cyangwa igitutu, ntibikora neza, kuburyo abaganga bakoresha sponges. Urashobora guhita ubishyira ahantu hava amaraso, hanyuma bagatangira kubyutsa imitsi no gutanga ubufasha bwubukanishi.
iIbyiza Kurindi Ibicuruzwa
Ugereranije sponges ya hemostatike nibindi bicuruzwa, ibikurikira ninyungu zimwe zo gukoresha ibikoresho nka chitosan na gelatine:
ü Hemostasis yihuse hamwe no kwinjirira cyane no kwihuta kwamaraso.
ü Umutekano na biocompatible hamwe ningaruka nke ziterwa ningaruka mbi.
ü Gutezimbere kuvugurura no gukira ibikomere neza.
iKoresha mu kubaga amagufwa
Byongeye kandi, zikoreshwa muburyo bwo kubaga amagufwa. Mugihe cyo kubaga, bakora neza kugirango birinde gutakaza amaraso. Hagati aho gukurura hemostatike gelatin spongeigamije gukuramo ubuhehere cyangwa amaraso byose hamwe nuburyo bwayo kugirango bigabanye kuva amaraso.
iKoresha muburyo bw'amenyo
Ubutaha bwo gukoresha sponges ya hemostatike irashobora kandi gukoreshwa mugubaga amenyo nko gukuramo amenyo, kubaga igihe, nibindi bikorwa byo kubaga umunwa. Ubushobozi bwabo bwo kugenzura amaraso biratangaje muri uku kubaga bigoye.
iIngaruka mubikorwa byo kubaga bitandukanye
Ubwanyuma, ibi gukurura hemostatike gelatin spongeikora neza kubikenewe bitandukanye. Nyamara, ubushobozi bwayo bwo guhagarika amaraso yumuntu nibyingenzi mubumenyi bwubuvuzi kubera kubikoresha; ni inyangamugayo. Ibikorwa nyamukuru byo kubaga bikoreshwa harimo abagore, neurologiya, otolaryngology, hamwe no kubaga rusange.
Umwanzuro
Rero, iyi yari ingingo ivuga kubyo sponges ya hemostatike ikozwe. Twizere ko, uzabona ibisubizo byose washakaga. Hagati aho, Itanga inyungu zitandukanye mubice bitandukanye bya siyanse yubuvuzi nko kubaga, kandi imbaraga zayo ni uguhagarika kuva amaraso menshi mukunyunyuza amazi.
Abashakashatsi baracyashakisha uburyo bushya bwo gukoresha ejo hazaza mu buvuzi no kurokora ubuzima bwinshi.
