Mu mibiri y'abantu,kolagenni ngombwa nkumutima mumubiri.Iradufasha gukomeza kuba muto no kugira ubuzima bwiza.Iyo tuvutse, kolagen iba iri hejuru, ariko uko tugenda dusaza, kubura kolagen bibaho, kandi tugasaza.Ariko, gusaza birashobora gutinda ufata inyongeramusaruro za kolagen.Ariko ikibazo hano ni ubwoko 28 bwa Collagen mumubiri, kandi birakenewe cyane kumva ubwoko bukora iki kugirango tutarenza urugero kubundi bwoko.Noneho, soma kugirango ukomeze kuba muto kandi ufite ubuzima bwiza.
Igishushanyo-oya-1-Ubwoko-bwa-Kolagen
Urutonde
1.Ni iki Collagen?
2.Ni gute imikorere ya kolagen mu mubiri?
3.Uburyo bwa Collagen: Ni ubuhe bwoko butandukanye?
Ati: "Nkuko umusatsi wacu ukura bisanzwe, Collagen ni poroteyine umubiri wacu ukora buri gihe."
Igishushanyo no 2-icyo-ni-kolagen
Biratangaje kumenya ko mumubiri wumuntu, hafi 30% yikigereranyo cya proteine gifitwe na Collagen, kandi ugereranije numubiri wose, proteyine zigize 14 ~ 16%.Collagen irahari hose, nkumwuka mwisi;kurugero, urashobora kubisanga mubice, kumara amara, amagufa, uruhu, nibindi bice byose byumubiri wumuntu.
2) Collagen ikora iki mumubiri?
Ibikurikira ninshingano za Collagen mumubiri wacu:
Igishushanyo no 3 Ni uruhe ruhare rwa kolagen mu mubiri.
✓Mu ruhu -ikomeza yoroshye, yoroheje, ikomeye, hamwe nimpu-nke.
✓Igice cyo hejuru ku ngingo & amara - Kora nk'urwego rukingira
✓Imbere mu magufa - ifasha mu gukora amagufwa, yongera ubucucike, kandi itinda osteoporose
✓Mu ngingo - ifasha muburyo bwabo iyo ikora nkumugereka & ingingo zikurura
✓Imisumari -Kolagen ikora keratin, hanyuma ikora imisumari.Noneho, Collagen ishinzwe gukura imisumari nubuzima
✓Umusatsi -Poroteyine y'ibanze, keratin, mu musatsi, ikomoka kuri aside amine runaka ya Collagen, cyane cyane, Collagen ikora umusatsi.Byongeye kandi, urwego rwa dermis, aho imisatsi (imizi) ihari, ikozwe muri Collagen.
✓Amaraso -Fibre ya kolagen irahari munsi yimbere yimbere yimiyoboro yamaraso muburyo bwurusobe.Byongeye kandi, batanga infashanyo yuburyo, kandi mugihe cyimvune, bakora nka rukuruzi yo gukiza no gufasha gusana.
✓Hagati y'imitsi -kora nk'imitsi y'imitsi, igumane hamwe kandi itange ingirabuzimafatizo.Bakora kandi nk'uburyo bwo kohereza imbaraga zandurira mu mitsi kugera kuri skeleti (amagufwa, imitsi, ligaments).
3) Ni ubuhe bwoko butandukanye bwa Collagen?
Igishushanyo no 4-Niki-ni-ubwoko-butandukanye-bwa-kolagen
Abahanga bavumbuye neza ubwoko burenga 28 bwaKolagenkandi bashyizwe mubikorwa bashingiye kubikoresho byabo byubaka, gahunda yimiterere, nibikorwa bakora.
Uhereye kuri ubu bwoko 28, hari Collagens 5 zifite ingaruka nyinshi, nka;
a) Ubwoko bwa Kolagen I.(byinshi cyane)
b) Ubwoko bwa Kolagen II
c) Ubwoko bwa Collagen III(byinshi cyane)
d) Ubwoko bwa Kolagen V.
e) Ubwoko bwa Kolagen X.
a) Andika I Collagen & Imikoreshereze yayo
“Ubwoko bwa I Collagen ni poroteyine ndende, inshuro eshatu, kandi ikozwe muri acide eshatu za amine: glycine, proline, na hydroxyproline.Ibisigazwa bya glycine bigize intandaro ya triple helix, mu gihe ibisigazwa bya protine na hydroxyproline bitanga guhinduka n'imbaraga. ”
Urashobora kugereranya akamaro k'ubwoko bwa I Collagen uhereye kumwanya wacyo wa 1 murwego rwo kwita izina kuko igizwe na 90% ya Collagen yose mumubiri wumuntu, cyane cyane muruhu, amagufwa, hamwe nuduce duhuza (tendons, ligaments, cartilage).
Gukoresha Ubwoko bwa I Kolagen
Nkuko Ubwoko bwa I Collagen ari bwinshi mu ruhu no mu magufa, urashobora kugereranya imikorere yacyo nyamukuru ni ugukomeza uruhu ruto kandi rukagumana imbaraga zamagufwa - ibisobanuro byatanzwe hano hepfo;
✓Ubuzima bwuruhu:Niba ufite iminkanyari, ubunebwe, cyangwa ububobere ku ruhu rwawe, noneho ikibazo cyacyo nyamukuru nukubura ubwoko bwa I Collagen.
✓Kugabanuka kw'imitsi: Ubwoko bwa I Collagen nabwo ni ngombwa mu kugabanya imitsi.Ifasha guhuza fibre yimitsi ikanabemerera kwandura no kuruhuka.
✓Imitsi y'amaraso:Ubwoko bwa I Collagen nabwo ni ingenzi mu mitsi y'amaraso.Ifasha gukora urukuta rw'imiyoboro y'amaraso kandi ikomeza gukomera no kugira ubuzima bwiza.
✓Gukiza ibikomere:Ubwoko bwa I Collagen nayo ni ngombwa mugukiza ibikomere.Ifasha gukora igisebe hejuru y igikomere kandi gitanga urwego rwo gukura kwimitsi mishya.
✓Gusana karitsiye:Ihuriro mu mubiri wumuntu rikozwe mubintu byoroshye byitwa karitsiye, kandi iyi karitsiye ikozwe mubwoko bwa I Collagen.Cartilage ikora nk'ikintu gikurura kandi kigabanya umuvuduko hagati y'amagufwa abiri.
✓Gukora amagufwa:Nta magufa, tumeze nk'igitambara kirekire kirambaraye hasi.Umubiri wacu ukora amagufwa ahanini ava mubwoko bwa I kolagen.Noneho, Ubwoko Bwinshi I Collagen bisobanura kubyara amagufwa meza, gukira vuba, hamwe nuburyo bukomeye bwamagufwa.
b) Ubwoko bwa II Collagen & Imikoreshereze yayo
"Ubwoko bwa II Collagen igizwe n'iminyururu itatu miremire ya aside amine ihujwe hamwe kugirango ikore inshuro eshatu.Triple helix itanga ubwoko bwa II Collagen imbaraga no guhinduka. ”
Iraboneka cyane muri karitsiye kandi ishinzwe gutanga imbaraga no guhinduka.Ubwoko bwa II inyongera ya kolagen ikozwe mubikoko cyangwa inkoko.
Gukoresha Ubwoko bwa II Collagen
✓Ubuzima buhuriweho:Ubwoko bwa II Collagen ni nyinshi cyane muri karitsiye, birumvikana rero ko gufata inyongeramusaruro zayo bizafasha kuvura amagufwa & indwara zifata nka osteoarthritis, nibindi.
✓Ubuzima bwuruhu:Ubushakashatsi bumwe bwerekanye ko ubwoko bwa II bwa kolagen bushobora kugabanya isura yiminkanyari hamwe nimyaka yimyaka kandi bigafasha kunoza uruhu rworoshye.
✓Ubuzima bwiza:Ubushakashatsi bumwe bwakozwe bwerekanye ko ubwoko bwa II bwa kolagen bushobora gufasha kurinda imbere / imbere munda no kunoza igogorwa no kwinjiza intungamubiri.
✓Imikorere ya sisitemu:Ubwoko bwa II bwiyongera bwa kolagen nabwo rimwe na rimwe bukoreshwa mu gufasha sisitemu yumubiri kurwanya indwara, bikaviramo gukira vuba indwara.
c) Andika III Collagen & Imikoreshereze yayo
“Mu buryo, Ubwoko bwa IIIKolagenikozwe mu minyururu itatu isa na alfa, ikagira homotrimer, bitandukanye n'ubwoko bwa I Collagen, igizwe n'iminyururu ibiri ya alpha1 n'umunyururu umwe wa alfa2. ”
Iyo bigeze ku bwoko bwa III kolagen, ni icyiciro cya 2 cyinshi cya Collagen mu mubiri w'umuntu.Ikwirakwizwa cyane mubice bitandukanye nk'inda, imiyoboro y'amaraso, nyababyeyi, uruhu, hamwe n'ingingo.Dukurikije imibare yaturutse mu bice bitandukanye byumubiri wumuntu, byanditswemo Ubwoko bwa I kugeza Ubwoko bwa III Igereranya rya Collagen ni nka 4: 1 (uruhu), 3: 1 (ingingo), nibindi.
Ubu bwoko bwa Collagen, bushyirwa muri fibrillar, bukora fibre ndende, yoroheje itanga ingirabuzimafatizo n'imbaraga.Byongeye, ifasha kandi ibikomere gukira vuba.Byongeye kandi, ikomeza imyubakire yimiyoboro yamaraso nizindi ngingo, ifasha imikorere yabyo.
Gukoresha Ubwoko bwa II Collagen
✓Ubuzima buhuriweho:Ubwoko bwa III Collagen ntabwo ari nyinshi mumagufa na karitsiye, ariko irahari kandi ifasha gushyigikira ubundi bwoko bwa karitsiye kugirango igumane imbaraga nubuzima.
✓Ubuzima bwuruhu:Ubwoko bwa III Collagen ni nyinshi cyane mu ruhu, kimwe na Type I Collagen, kandi ifasha uruhu kwirinda imirongo myiza, nyuma ihinduka iminkanyari.Byongeye, Ubwoko bwa III Collagen ikora urusobe rwubatswe munsi yuruhu kugirango uruhu rukomeze, ariko nkuko Collagen yoroshye, uruhu rukomeza kurambura.
✓Ubuzima bwimisatsi: Tpye III Collagen itanga ibikoresho fatizo byo gukora umusatsi, kubwibyo ahanini byongera imisatsi n'imbaraga.Byongeye kandi, Ubwoko bwa poroteyine ya III iboneka no mu mutwe aho imizi yimisatsi ihari.Muri make, gufata Ubwoko bwa III bwa kolagen bizafasha umuntu ufite umusatsi udakomeye.
✓Gukiza ibikomere:Ubwoko bwa III nubwa kabiri poroteyine nyinshi ya Collagen mu mitsi no mu ngingo, kandi nkuko mubizi, Collagen ni rukuruzi isanzwe yo gukiza ingirabuzimafatizo;mugihe habaye igikomere, Collagen ifasha gukora ingirangingo nshya vuba.
✓Ubudahangarwa:Ubwoko bwa III Collagen irashobora gufasha kongera ubudahangarwa mukubyara umusaruro wamaraso yera.Bikunze gukoreshwa mubyongeweho kuvura indwara ziterwa na autoimmune nizindi ndwara zumubiri.
d) Andika V Collagen & Imikoreshereze yayo
Ati: "Ubu bwoko bwa Collagen bwashyizwe mu rwego rwa fibrillar, buboha mu mbaho ndende, imeze nk'umugozi utanga imbaraga kandi zihindagurika ku myenda - ikorana na Type I na Type III Collagens, bigatuma habaho ingirabuzimafatizo ku ngingo no mu ngingo."
Ubwoko V Collagen ntabwo ari bwinshi nkibindi bisigaye bitanu byingenzi bya Collagen, ariko ikora imirimo ikomeye nko gukora cornea yijisho, ibice byuruhu & umusatsi, hamwe nuduce twinshi.Ikorera muri matrice idasanzwe yingirangingo zinyuranye, nkuruhu, amagufwa, imiyoboro yamaraso, hamwe na plasita, itanga ubufasha bukomeye bwubaka.
Gukoresha Ubwoko bwa II Collagen
✓Umusatsi n'imisumari:Ifasha ubuzima nubukomezi bwimisatsi nimisumari.
✓Ubuzima bw'amaso:Nibintu byingenzi bigize cornea, bigira uruhare mukubungabunga imiterere yijisho no kumvikana.
✓Kurwanya uruhu:Ubwoko V Collagen ifasha mukubungabunga ubuzima bwuruhu, igira uruhare mukubera imbaraga no gukomera.
✓Amaraso: Ubwoko bwa V Collagen ikora imiterere yinkuta zamaraso, bigira uruhare mugukomeza no gukora neza.
✓Imiterere y'imyenda: Ubwoko bwa V kolagen ifasha ubundi bwoko bwa kolagen mugukora ingirangingo zitandukanye hamwe ningingo zingingo, bityo bifasha mumikurire yabo myiza.
e) Andika X Collagen & Imikoreshereze yayo
"Ubwoko bwa X Collagen bugizwe na triple ya helix ya Collagen yegeranye na domaine ebyiri zidakorana, NC2 na NC1."
Ifasha mu guhuza imyunyu ngugu ya ngombwa, nka calcium, kuri fibre ya Collagen, kongera imbaraga z'amagufwa - kubikora, bigira uruhare mu gukomera kwa sisitemu yacu.
Bitandukanye nubundi bwoko bwa Collagen, ntabwo ikora fibre ndende ahubwo ikora urusobe rwibintu bigufi.Uru rusobe rutandukanye rutanga imbaraga nubworoherane ku isahani yo gukura hamwe nubutaka bwabazwe bwa articular artilage.
Gukoresha Ubwoko bwa II Collagen
Ibikurikira nuburyo bumwe bwo gukoresha Ubwoko X Collagen;
✓Uruhare rwihariye:Nubwo iboneka ku rugero ruto, imikorere yayo itandukanye mu iterambere rya skeletale yerekana akamaro kayo.
✓Ibimenyetso by'inzibacyuho:Ubwoko X Collagen ikora nk'ikimenyetso mugihe cyo gukura kw'amagufwa, byerekana ihinduka riva muri karitsiye igufwa rikomeye.
✓Ikimenyetso cyerekana imikurire:Kuba iri mu isahani yo gukura byerekana ihinduka rikomeye rishimangira gukura kw'amagufwa maremare.
✓Ushinzwe iterambere:Mu gufasha iyi nzibacyuho, Ubwoko X Collagen butuma amagufwa akura haba muburebure n'imbaraga, zikenewe mubuzima bwiza bwamagufwa nubusugire bwimiterere.
Umwanzuro
Inganda za kolagenkwisi yose ikora inyongera zihariye zibanda kubyara ubwoko bwihariye bwa Collagen, nkubwoko bwa I cyangwa Ubwoko bwa II nibindi.Ariko, ni ngombwa kumenya ko bamwe aribyobovine, bamwe ni ingurube, mugihe abandi bakoresha ibice byinyamanswa bivanze - bishobora kuba ikibazo mubyiza no mumico imwe n'imwe (ingurube Collagen ni haram muri Islam).
Ariko, twe kuri Yasin dufite intego yo gukora Collagen mubwoko bwose bwinyamanswa ariko mubikoresho byihariye kugirango abakiriya babone ibyo bakeneye.Noneho, niba uri mubatanga protein cyangwa abatanga ifu ya kolagen, turashobora kwemeza ko ubona ibicuruzwa byukuri 100%.
Igihe cyo kohereza: Nzeri-08-2023